A medical food with IBS-Defense™, a unique combination of clinically proven probiotics and a low-FODMAP prebiotic, for the dietary management of IBS*
Reduce IBS symptoms by up to 79%*

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Clinically Studied Probiotics and Sunfiber ® Prebiotic to Help Reduce Constipation, Diarrhea, and Abdominal Pain.†*

THER-BIOTIC®PRO IBS RELIEF is a medical food for the dietary management of IBS. It works by addressing  nutrient absorption issues common in many people with IBS that cannot be resolved by normal diet modification alone. It works by addressing nutrient absorption issues common in many people with IBS that cannot be resolved by normal diet modification alone. It is not a replacement for any medication. USE UNDER MEDICAL SUPERVISION. A prescription is not required for purchase.

Benefits & Features:

  • Significantly reduces constipation and diarrhea
  • Naturally relieves gas, bloating, and abdominal pain
  • 20B CFU clinically studied probiotics per serving
  • Contains Sunfiber® – a Low FODMAP CertifiedTM prebiotic that is gentle enough for people with IBS†
  • Uses InTactic® technology to protect probiotics from stomach acid so they an survive to reach the intestine
  • Shelf-stable for convenience through formulation and utilization of patented desiccant-lined packaging
  • Manufactured without common allergens, so even those with food sensitivities can safely take it
  • Non-GMO | Vegetarian | Contains no synthetic colors, flavors, or preservatives

Directions: For ages 18+, 1 capsule daily or as directed by your healthcare professional.

Ingredients: 20 Billion CFU – (L. plantarum, L acidophilus, B. lactis), Sunfiber® (partially hydrolyzed guar gum), InTactic® (proprietary polysaccharide complex), stearic acid, and vegetarian capsule (hydroxypropyl methylcellulose, water).

Each capsule contains 10 mg sodium and 10 mg potassium. Not a significant source of any other essential nutrient.

Allergy statement: Manufactured without the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans.

Storage: Store at room temperature (59°-85° F).

Caution: Consult with your physician if you are pregnant or lactating, have a medical condition, taking prescription drugs, or under the age of 18 years. KEEP OUT OF REACH OF CHILDREN.

Sunfiber® is a registered trademark of Taiyo International, Inc.


Is there clinical evidence to support the use of these probiotics in individuals with IBS?

The health effects of probiotics vary between different species and strains.¹ When selecting a probiotic formula for the dietary management of IBS, it is important to choose probiotic strains which have been clinically shown to be beneficial for individuals with IBS.

In clinical trials, the three probiotic strains included in Ther-Biotic Pro™ IBS Relief’s unique IBS-Defense™ formulation have been shown on average to reduce IBS symptoms and/or normalize bowel habits in individuals with IBS.† 2-5 One of these strains was shown to provide a:†4

+ 79% reduction in the severity of constipation + 67% reduction in abdominal pain severity∆      + 70% reduction in the severity of diarrhea         + 110% improvement in mental well-being


For probiotics to be effective, adequate amounts of the bacteria must survive the conditions of the gastrointestinal tract and be delivered to the large intestine where they can have the most profound effect on human health. To protect the probiotics during their journey to the large intestine, Ther-Biotic Pro™ IBS Relief utilizes Ther-Biotic®’s proprietary InTactic® technology. This innovative, acid-stable technology forms an additional layer of protection around the encapsulated probiotics. Once exposed to gastric acid in the stomach, the outer layer of the capsule begins to dissolve. Afterwards, the inner layer of InTactic test, composed of a polysaccharide complex, forms an insoluble matrix that remains intact until the probiotics enter the small intestine. After a few hours, the increase in pH and movement of the intestinal walls degrade the protective layer, releasing the live probiotics where their influence on gastrointestinal health can be most influential.

Ther-Biotic Pro™ IBS Relief has been specially formulated for the dietary management of IBS. When Not all strains are the same: the effects vary between different bacterial species and strains.1 Only Ther-Biotic Pro™ IBS Relief contains IBS-Defense™, a unique combination of 3 probiotics clinically proven to significantly reduce IBS symptoms, combined with a low-FODMAP compliant prebiotic, and protected by InTactic® technology. Combining probiotics and a prebiotic into one convenient, comprehensive formulation enhances the beneficial actions of each of these nutrients, leading to entourage benefits. Furthermore, the low-FODMAP prebiotic within Ther-Biotic Pro™ IBS Relief—partially hydrolyzed guar gum (PHGG)—was specially selected for patients with IBS. Unlike many other prebiotics, which may cause gas, bloating, and discomfort, PHGG is well-tolerated by people with IBS. Lastly, Ther-Biotic Pro™ IBS Relief uses our proprietary InTactic® technology to protect the probiotics from destruction by gastric acid, digestive enzymes, and bile acids, facilitating the delivery of live bacteria to the large intestine.

Medical foods are specially formulated and intended for the dietary management of a disease or condition that has distinctive nutritional needs which cannot be met through normal diet modification alone. Because patients who use these solutions have health conditions that require on-going medical management, medical foods are to be used under the supervision of a healthcare practitioner. In the case of IBS, the complex gastrointestinal disruptions result in distinctive nutritional requirements. Specifically, consumption of components that directly impact the bacterial community within the gut, such as probiotics, have been shown to positively affect IBS symptoms.6,7 In contrast, increased consumption of foods in their natural state which contain live or active bacterial cultures, such as yogurt, may not provide enough bacteria that survive to the intestine to confer health benefits. Ther-Biotic Pro™ IBS Relief has been specially formulated to contain ingredients that address the distinctive nutritional needs of IBS, which cannot be met through the modification of the normal diet alone.

Ther-Biotic Pro™ IBS Relief is free from common allergens such as dairy, gluten, yeast, soy, peanuts, tree nuts, wheat, eggs, fish, and shellfish. Additionally, Ther-Biotic Pro™ IBS Relief does not contain any artificial flavors, sweeteners, coloring, preservatives, and is non-GMO.

Partially hydrolyzed guar gum (PHGG) is a prebiotic that is a water-soluble, galactomannan (not starch or sugar-based). Prebiotics support the survival, activity, and growth of beneficial bacteria. When consumed by individuals with IBS, PHGG has been demonstrated to help increase the number of beneficial bacteria and production of short-chain fatty acids in the intestine.8,9 Importantly, PHGG is a low-FODMAP prebiotic: it provides a supportive effect by providing entourage benefits that occur when probiotics are combined with a prebiotic, with minimal bloating, gas, and discomfort, which other, short-chain prebiotics—like FOS and GOS—may cause.

Yes, Ther-Biotic Pro™ IBS Relief is low-FODMAP compliant. It is well known that individuals following a lowFODMAP diet may have reduced numbers of Bifidobacteria due to decreased intake of prebiotic fibers, so a probiotic product containing this bacteria can help maintain levels in the gut.10 Additionally, Ther-Biotic Pro™ IBS Relief contains PHGG, a low-FODMAP prebiotic to help nourish the beneficial bacteria in the GI tract with minimal bloating, gas, and discomfort, which other, short-chain prebiotics—like FOS and GOS—may cause.

Ther-Biotic Pro™ IBS Relief is a medical food for the dietary management of IBS. It is formulated to help relieve the severity and frequency of IBS symptoms in adults (18 and older). Ther-Biotic Pro™ IBS Relief may be used by individuals with all IBS subtypes including IBS-M, IBS-C, and IBS-D. Because patients who use these solutions have health conditions that require on-going medical management, medical foods are to be used under the supervision of a healthcare practitioner.

To support increased survival, it is recommended to take probiotics during the first part of a meal. Gastric acid is temporarily buffered with food. Thus, taking probiotics when stomach acid levels are lower can help ensure that more healthy bacteria survive and populate the large intestine. Additionally, this allows the beneficial bacteria to be among the first gastric contents released into the small intestine. To further promote survivability, Ther-Biotic Pro™ IBS Relief uses InTactic® technology to protect the beneficial bacteria as they transit the gastrointestinal tract.

Ther-Biotic Pro™ IBS Relief contains live probiotic bacteria. Antibiotics, which destroy both beneficial and unfriendly bacteria, can also target probiotics. To help the probiotics arrive alive, it is recommended to take probiotics at least 2 hours before or after taking antibiotics. If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product. Keep out of reach of children.

In clinical studies, long-term use (12 weeks) of the probiotics in Ther-Biotic Pro™ IBS Relief was well-tolerated.3,4 However, duration should be tailored to each individual.

In the clinical studies investigating the efficacy of the probiotic strains in Ther-Biotic Pro™ IBS Relief, on average, most individuals with IBS reported significant improvement in symptoms after 4 weeks of use.2,4,5 In one study, after 4 weeks of probiotic use, over 75% of individuals with IBS reported an “excellent” or “good” improvement in their IBS symptoms, compared to 8.1% in placebo group.†2 Another study, which tested probiotic use for a longer duration of 12 weeks, found that as the length of use increased, so did the percentage of participants who experienced improvement in symptoms.†4 Indeed, after 12 weeks, over 80% of individuals reported a significant improvement in overall symptoms.†4 Due to differences in diet, lifestyle, and overall health, the length of use needed to notice an improvement in IBS symptoms may vary between individuals.

Ther-Biotic Pro™ IBS Relief has been formulated to maintain the label value of 20 billion CFU at room temperature throughout its shelf life. Although refrigeration is not necessary, storing Ther-Biotic Pro™ IBS Relief in the refrigerator may extend the product’s shelf life.

Many factors, such as light, heat, and moisture, may compromise the survivability of probiotics during manufacturing, storage, and delivery to the human gastrointestinal tract. To safeguard its live probiotic strains from these elements, Ther-Biotic Pro™ IBS Relief was formulated based on the latest research. The probiotics in Ther-Biotic Pro™ IBS Relief are protected against:

+ Moisture: The interior of the Ther-Biotic Pro™ IBS Relief bottle is lined with a desiccant, which absorbs moisture. Additionally, after the probiotics are packaged, the bottle is sealed with an engineered leakproof seal to prevent moisture infiltration. These technologies reduce the impact of moisture to ensure survivability of probiotics during manufacturing, packaging, and storage.

+ Light: The opaque bottle shields the probiotics from damaging exposure to light.

+ Heat: Ther-Biotic Pro™ IBS Relief was specifically formulated to contain bacterial strains that have been demonstrated to retain viability at room temperature over a longer period of time.

+ Stomach Acid: Ther-Biotic®’s proprietary InTactic® technology protects the probiotics from stomach acid, digestive enzymes, and bile salts. This allows for the targeted release of probiotics within the intestines, where the influence of probiotics is most profound.



Give your digestive tract a break

Intermittent fasting may help relieve IBS symptoms because it allows your digestive tract to rest. Digestive rest is needed to activate the MMC (migratory motor complex), which moves food through the GI tract and supports healthy elimination. Fasting can also initiate important repair processes, helps regulate insulin and blood sugar levels, and upregulates genes related to longevity. Eating large portions, hurrying through mealtime, and partaking in mid-night snacking can hinder healthy digestive function by not allowing your body enough time to properly process the food you
are eating. The 16/8 method is a common approach for those new to intermittent fasting- restricting your daily eating window to 8 hours, such as 11a.m–7 p.m. Then you fast for 16 hours in between. It is important to experiment and find a method that works for you. However, always consult a physician before starting any fasting regimen. Fasting is not recommended for pregnant or underweight individuals.


Prioritize Relaxation & Self-Care

There are many complex connections between the brain and the gut. Psychological factors, the nervous system, and muscle contractions in the gut all interact with each other. This is known as the brain-gut axis. So, if you have a hectic lifestyle, stress and anxiety may also be causing or encouraging IBS symptoms. There are many practices that can help balance mental emotional health and in return may help calm IBS symptoms. Some stress-management techniques to explore include:
+ Create time for relaxation and self-reflection.
+ Make the most out of leisure time.
+ Relaxation therapies such as Emotional Freedom Technique (EFT) and mindfulness meditation.
+ Exercise – yoga or taking a walk.
+ Seek support or counselling.



Track Your Diet & Lifestyle Activities

Since each person’s experience with IBS is so different, it’s useful to keep track of your symptoms and possible triggers. Remember symptoms may not be caused by the food you have just eaten, but what you ate earlier that day or the day before. Keeping a food and symptom diary can help you to start noticing patterns of how your diet affects your symptoms. You can use this information to explore your eating patterns and triggers and can share this information with your healthcare provider to create a diet plan that uniquely supports your body’s needs.


Participate in Regular Movement

Getting the body moving is a great way to promote healthy bowel function and regularity. Additionally, daily movement or exercise is a great way to relieve stress and anxiety, as well as dissipate built up tension in the body – which, for many of us tends to impede the proper function of our stomach and intestines. Walk, swim, jog, dance – there are many ways to move, but most importantly is that you enjoy the activity.

Make Quality Sleep a Priority

Unlike sleep quantity, sleep quality refers to how well you sleep. Disrupted circadian rhythms increases the likelihood of increased GI symptoms, so getting in sync with your body’s natural sleep-wake cycle, or circadian rhythm, is one of the most important strategies for sleeping better. One easy way is by going to sleep and get up at the same time every day. By obtaining adequate sleep
gives added benefit to bodily rejuvenation and mental-emotional wellbeing.


Check For Other Contributors

If you feel like your IBS symptoms are suddenly flaring, think about any medications you have taken recently. Some OTC and prescription medicines appear to make IBS symptoms worse in some people.  Weigh the pros and cons of any medication you’re taking that might affect your IBS with your doctor.


FDA Disclaimer†*: None of these statements have been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any diseases.

Notes: You should consult a licensed health care professional before starting any supplement, dietary, or exercise program, especially if you are pregnant or have any pre-existing injuries or medical conditions.