Description

Saccharomyces Boulardii

10 Billion CFU per serving

• For Occasional Diarrhea*
• Supports a Healthy Balance of Intestinal Flora*

How it Works

The intestinal epithelium forms a continuous physical and functional barrier that protects the internal environment of the body from the fluctuating external input. Various substances including dietary elements, gastrointestinal secretory products, and xenobiotics are known to disrupt this epithelial barrier, leading to the shedding of epithelial cells and the development of digestive upset and discomfort. Saccharomyces boulardii is a probiotic yeast that helps to support intestinal health by encouraging a balanced response by the intestinal epithelium to normal metabolic stress, as well as through its effects on overall gut ecology.* Saccharomyces boulardii has been clinically shown to support gastrointestinal health during temporary disruptions in the normal balance of gut flora.* The probiotic strain in this product has been identity-verified using DNA-fingerprinting technology.

                                                                                          

Saccharomyces Boulardii

TECHNICAL SUMMARY
The intestinal epithelium forms a continuous physical and functional barrier that protects the internal environment of the body from the fluctuating external input. Various substances including dietary elements, gastrointestinal secretory products, and xenobiotics are known to disrupt this epithelial barrier, leading to the shedding of epithelial cells and the development of digestive upset and discomfort. Saccharomyces boulardii is a probiotic yeast that helps to support intestinal health by encouraging
a balanced response by the intestinal epithelium to normal metabolic stress, as well as through its effects on overall gut ecology.* Saccharomyces boulardii has been clinically shown to support gastrointestinal health during temporary disruptions in the normal balance of gut flora.*

Strain Information: Saccharomyces boulardii belongs to a family of eukaryotic cells similar to fungi and algae. This yeast possesses many properties that support its use as a probiotic agent, including high survivability throughout the GI tract due to its range of pH tolerance and its optimum temperature of 37˚C.

Allergen and Additive Disclosure: Not manufactured with wheat, gluten, soy, corn, milk, egg, fish, shellfish, or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Delivery Form: Vegetable capsules.

ROLE AS NUTRIENT/FUNCTION
Probiotics support the non‐immunologic gut defense system by stabilizing the gut microflora and the immunologic gut defense system by enhancing the gut’s humoral immune responses.* Saccharomyces boulardii interacts with environmental stressors directly and/or by interfering with their ability to pass through the digestive barrier.* S. boulardii also has the ability to increase production of short‐chain fatty acids, especially butyrate, and to enhance digestive mucosa’s ability to respond to local
biological stress.*

NATUROKINETICS®

Liberation: Disintegration of the vegetable capsule is measured in water using a USP testing method with disintegration between zero and 60 minutes.

Absorption: Probiotics are not absorbed and do not reach the blood stream in healthy individuals. Laboratory studies have shown S. boulardii does not pass into intestinal cells and is therefore not absorbed into the body.

Distribution along the GI Tract: With daily ingestion, S. boulardii is able to persist along the entire gastrointestinal tract. This yeast is resistant to gastric acids and to bile secretions. Pharmacokinetics studies indicate that after ingestion, S. boulardii is able to quickly reach high concentrations in the colon without colonizing it.

Elimination: Probiotics are eliminated in feces. S. boulardii typically is cleared from the stool 2‐5 days after discontinuation of supplementation.

SAFETY INFORMATION
Tolerability: S. boulardii is generally well tolerated. Occasionally, S.boulardii may cause flatulence. Rarely, oral use of S.boulardii has been associated with fungemia in both immunocompromised and immunocompetent patients with most of the cases associated with indwelling catheters in critically ill intensive care unit patients when packets or capsules with S. boulardii were opened at bedside.

Contraindications: Use with caution in cases of severe immunodeficiency.

Do not use if allergic to yeast.

INTERACTIONS

Drug Interactions: Theoretically, since S. boulardii is a yeast, antifungals might decrease its effectiveness.
Supplement Interactions: None known.
Interaction with Lab Tests: None known.

STORAGE
Store in a cool, dry place. Refrigeration recommended to maintain freshness.

FDA Disclaimer†*: None of these statements have been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any diseases.

Notes: You should consult a licensed health care professional before starting any supplement, dietary, or exercise program, especially if you are pregnant or have any pre-existing injuries or medical conditions.